Crash: A Memoir of Overmedication and Recovery is the story of a Helen Dempsey and her daughter Ann who both fall victim to the same regimen of overmedication at the hands of the mental health system. Helen struggles with intractable depression and initially turns to self-medication with alcohol, but finds herself unable to recover despite numerous drugs, hospitalizations, and electroconvulsive therapy. Ann vows to build a different life for herself, but eventually descends into the pain of a mysterious migraine and intractable darkness lasting for many years.

Severely overmedicated with opioids and psychiatric drugs, Ann crashes her car twice. Because traditional medical treatments have failed her, she challenges her doctors' advice and discovers ways to heal the source of her physical and emotional pain without drugs. The question of why her mother never got well continues to haunt her long after her mother's death until she finds the missing puzzle pieces she'd searched for all her life stashed in a dusty box in her sister's attic.