A thorough look at the different research applications of temporal pattern detection and analysis using specially developed software, THEME (TM). The T-system is a model for discovering hidden recurring patterns in observable behavior and can be useful to researchers in neuroscience, psychology, biology, robotics, finance, medicine, and many other fields. This system forms the basis for the search algorithms in THEME (TM) , now in its 6th edition and available in both educational and fully commercial versions. Each chapter describes the methodology used and discusses the findings in detail, providing a highly useful primer for advanced students and researchers.