Early in the 21st Century the Tyrell Corporation advanced Robot evolution into the Nexus phase - a being virtually identical to a human - known as a Replicant. Replicants were used Off-world as slave labor, in the hazardous exploration and colonization of other planets.Now, on Earth, the Nexus 4 Replicants have been adapted for societal elites to own for industry and service work. But, Tyrell continues to experiment with further enhancements - because progress stops for no man.LAPD Detective Cal Moreaux has discovered that the suicide of Dr. Lydia Kine was actually an elaborate ruse constructed by the Tyrell Corp engineer so she could live freely as a Replicant named Asa. Dr. Kine's latest experiment - the escaped Nexus 5 prototype - initially received the blame for her death, however Cal has discovered the truth - the identity of the Nexus 5's host consciousness: his sister, Nia Moreaux.More existentially advanced than the others, Nia has been "e;awakening"e; some Replicants in the slums of Los Angeles, causing them to leave their positions of servitude in pursuit of autonomy. Tyrell Corp executive, Ilora Stahl has been charged with overseeing Cal and the Nexus 5's capture, and she will stop at nothing to protect her job and the company's brand in spite of this chaos.Asa has finally terminated the deranged Nexus 4 that's been terrorizing citizens and Replicants alike, but the score between he and Nia has yet to be fully settled. After realizing there's a greater threat at play in the form of Ilora Stahl, Cal, Asa, Nia, and a few loyal "e;awakened"e; Replicants have banded together to save the residents of Sector-6B from Ilora's rage-fueled destruction.